DERA Gene Summary [Human]
Enables deoxyribose-phosphate aldolase activity. Involved in deoxyribonucleoside catabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | DERA |
| Official Name | deoxyribose-phosphate aldolase [Source:HGNC Symbol;Acc:HGNC:24269] |
| Ensembl ID | ENSG00000023697 |
| Bio databases IDs | |
| Aliases | deoxyribose-phosphate aldolase |
| Synonyms | 2010002D22RIK, 2500002K03Rik, CGI-26, DEOC, deoxyribose-phosphate aldolase, Dera-ps1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DERA often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- deoxyribose-phosphate aldolase
- DeoC/LacD family aldolase
- TIM-like beta/alpha barrel domains
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- secretory granule lumen
- ficolin-1-rich granule lumen
- Extracellular Space
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DERA gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pentose-phosphate shunt
- carbohydrate catabolic process
- deoxyribonucleoside catabolic process
- deoxyribonucleotide catabolic process
- deoxyribose phosphate catabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
- secretory granule lumen
- extracellular region
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- deoxyribose-phosphate aldolase activity
- protein binding