Dera Gene Summary [Mouse]

Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process; deoxyribonucleoside catabolic process; and deoxyribonucleotide catabolic process. Predicted to be located in nucleoplasm. Orthologous to human DERA (deoxyribose-phosphate aldolase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Dera
Official Name
deoxyribose-phosphate aldolase (putative) [Source:MGI Symbol;Acc:MGI:1913762]
Ensembl ID
ENSMUSG00000030225
Bio databases IDs NCBI: 232449 Ensembl: ENSMUSG00000030225
Aliases deoxyribose-phosphate aldolase (putative)
Synonyms 2010002D22RIK, 2500002K03Rik, CGI-26, DEOC, deoxyribose-phosphate aldolase, Dera-ps1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dera often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • deoxyribose-phosphate aldolase
  • DeoC/LacD family aldolase
  • TIM-like beta/alpha barrel domains
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • glaucoma
  • amenorrhea
regulated by
  • tetradecanoylphorbol acetate
  • genomic DNA
regulates
  • D-glucose
  • deoxyribonucleoside

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • secretory granule lumen
  • ficolin-1-rich granule lumen
  • Extracellular Space
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dera gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • pentose-phosphate shunt
  • carbohydrate catabolic process
  • deoxyribonucleoside catabolic process
  • deoxyribonucleotide catabolic process
  • deoxyribose phosphate catabolic process

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • secretory granule lumen
  • extracellular region
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • deoxyribose-phosphate aldolase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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