SNX29 Gene Summary [Human]
Predicted to enable phosphatidylinositol binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | SNX29 |
| Official Name | sorting nexin 29 [Source:HGNC Symbol;Acc:HGNC:30542] |
| Ensembl ID | ENSG00000048471 |
| Bio databases IDs | |
| Aliases | sorting nexin 29 |
| Synonyms | 4933437K13Rik, A-388D4.1, Gm11170, Gm1737, Gm930, LOC101929304, LOC687335, RGD1565890, RUNDC2A, sorting nexin 29 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNX29 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- domain involved in Ras-like GTPase signaling
- The Phox Homology domain, a phosphoinositide binding module
- RUN domain
- PX domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- schizophrenia
- major depression
- non-insulin-dependent diabetes mellitus
- Alzheimer disease
- metabolic syndrome X
- idiopathic scoliosis
- pervasive developmental disorder
- psychosis
regulated by
- L-triiodothyronine
role in cell
- transformation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNX29 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol binding