MON2 Gene Summary [Human]
Predicted to be involved in Golgi to endosome transport. Located in early endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MON2 |
| Official Name | MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:HGNC Symbol;Acc:HGNC:29177] |
| Ensembl ID | ENSG00000061987 |
| Bio databases IDs | |
| Aliases | MON2 homolog, regulator of endosome-to-Golgi trafficking |
| Synonyms | 2610528O22Rik, mKIAA1040, MON2 homolog, regulator of endosome-to-Golgi trafficking, RGD1308808, Sf21 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MON2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-terminal region of Mon2 protein
- Guanine nucleotide exchange factor in Golgi transport N-terminal
- protein binding
- dimerization and cyclophilin-binding domain of Mon2
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MON2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
- Golgi to endosome transport
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding