Mon2 Gene Summary [Rat]

Predicted to be involved in Golgi to endosome transport. Predicted to be located in early endosome membrane. Orthologous to human MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mon2
Official Name
MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:RGD Symbol;Acc:1308808]
Ensembl ID
ENSRNOG00000004185
Bio databases IDs NCBI: 314894 Ensembl: ENSRNOG00000004185
Aliases MON2 homolog, regulator of endosome-to-Golgi trafficking
Synonyms 2610528O22Rik, mKIAA1040, MON2 homolog, regulator of endosome-to-Golgi trafficking, RGD1308808, Sf21
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mon2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • C-terminal region of Mon2 protein
  • Guanine nucleotide exchange factor in Golgi transport N-terminal
  • protein binding
  • dimerization and cyclophilin-binding domain of Mon2

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • tinnitus
regulated by
  • lapatinib/pazopanib
regulates
role in cell
  • binding
  • production in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endosomal membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mon2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein transport
  • Golgi to endosome transport

Cellular Component

Where in the cell the gene product is active
  • early endosome membrane
  • extracellular vesicular exosome
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.