LAMB4 Gene Summary [Human]
Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to be located in basement membrane; extracellular region; and membrane. Predicted to be part of laminin complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LAMB4 |
| Official Name | laminin subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:6491] |
| Ensembl ID | ENSG00000091128 |
| Bio databases IDs | |
| Aliases | laminin subunit beta 4 |
| Synonyms | laminin subunit beta 4, laminin subunit β 4 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LAMB4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Laminin-type epidermal growth factor-like domai
- Laminin N-terminal (Domain VI)
- Mechanosensitive ion channel porin domain
- Ciliary protein causing Leber congenital amaurosis disease
- Synaptonemal complex protein 1 (SCP-1)
- C-terminal coiled-coil domain found in the laminin subunit beta (LAMB) family
- Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
- Growth-arrest specific micro-tubule binding
- ClyA-like
- EGF_CA
- Laminin EGF domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LAMB4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- basement membrane
- extracellular region