IGF2-AS Gene Summary [Human]
This gene is expressed in antisense to the insulin-like growth factor 2 (IGF2) gene and is imprinted and paternally expressed. It is thought to be non-coding because the putative protein is not conserved and translation is predicted to trigger nonsense mediated decay (NMD). Transcripts from this gene are produced in tumors and may function to suppress cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | IGF2-AS |
| Official Name | IGF2 antisense RNA [Source:HGNC Symbol;Acc:HGNC:14062] |
| Ensembl ID | ENSG00000099869 |
| Bio databases IDs | |
| Aliases | IGF2 antisense RNA, insulin-like growth factor 2 antisense 1 (non-protein coding), IGF2 antisense RNA 1 (non-protein coding) |
| Synonyms | IGF2 antisense RNA, IGF2-AS1, Igf2os, insulin-like growth factor 2, opposite strand, PEG8 |
| Species | Human, Homo sapiens |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm