RNF24 Gene Summary [Human]

This gene encodes an integral membrane protein that contains a RING-type zinc finger. The encoded protein may interact with multiple transient receptor potential cation channel subfamily C (TRPC) proteins and regulate the trafficking and insertion of these proteins into the plasma membrane. [provided by RefSeq, Mar 2016]

Details

Type
Protein Coding
Official Symbol
RNF24
Official Name
ring finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13779]
Ensembl ID
ENSG00000101236
Bio databases IDs NCBI: 11237 Ensembl: ENSG00000101236
Aliases ring finger protein 24
Synonyms 2810473M14RIK, 4930505A13Rik, D2Ertd504e, G1L, ring finger protein 24
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNF24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • Ring finger domain
  • protein binding
  • RING-H2 zinc finger domain
  • RING-like zinc finger
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • thoracic aortic aneurysms and dissections
  • drug-induced liver disease
  • cleft lip
regulated by
  • APP
  • lipopolysaccharide
  • prostaglandin E2
  • PTGER4

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RNF24 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • Golgi apparatus
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.