CEP126 Gene Summary [Human]
Involved in cilium assembly; cytoplasmic microtubule organization; and mitotic spindle organization. Located in centrosome; ciliary base; and midbody. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | CEP126 |
| Official Name | centrosomal protein 126 [Source:HGNC Symbol;Acc:HGNC:29264] |
| Ensembl ID | ENSG00000110318 |
| Bio databases IDs | |
| Aliases | centrosomal protein 126 |
| Synonyms | centrosomal protein 126, KIAA1377, mKIAA1377, RGD1563556 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CEP126 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Susceptibility to monomelic amyotrophy
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- midbody
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CEP126 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- mitotic spindle organization
- cytoplasmic microtubule organization
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
- midbody
Molecular Function
What the gene product does at the molecular level
- protein binding