RPF1 Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RPF1 |
| Official Name | ribosome production factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:30350] |
| Ensembl ID | ENSG00000117133 |
| Bio databases IDs | |
| Aliases | ribosome production factor 1 homolog, RNA processing factor 1, ribosome production factor 1 |
| Synonyms | 2210420E24Rik, 2310066N05Rik, BXDC5, ribosome production factor 1, ribosome production factor 1 homolog |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Brix domain
- protein binding
- The Brix domain is found in a number of eukaryotic proteins
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RPF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of 5.8S rRNA
- maturation of LSU-rRNA
Cellular Component
Where in the cell the gene product is active
- nucleolus
- preribosome, large subunit precursor
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- rRNA primary transcript binding