GUCY1B2 Gene Summary [Human]
Predicted to enable several functions, including GTP binding activity; guanylate cyclase activity; and heme binding activity. Predicted to be involved in cGMP-mediated signaling. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | GUCY1B2 |
| Official Name | guanylate cyclase 1 soluble subunit beta 2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:4686] |
| Ensembl ID | ENSG00000123201 |
| Bio databases IDs | |
| Aliases | guanylate cyclase 1 soluble subunit beta 2 (pseudogene) |
| Synonyms | GC-SB2, guanylate cyclase 1 soluble subunit beta 2 (pseudogene), guanylate cyclase 1 soluble subunit β 2 (pseudogene) |
| Species | Human, Homo sapiens |
Pathways
Biological processes and signaling networks where the GUCY1B2 gene in human plays a role, providing insight into its function and relevance in health or disease.
- Adrenomedullin signaling pathway
- Antiproliferative Role of Somatostatin Receptor 2
- Cellular Effects of Sildenafil (Viagra)
- Circadian Rhythm Signaling
- Corticotropin Releasing Hormone Signaling
- Dopamine-DARPP32 Feedback in cAMP Signaling
- Endothelin-1 Signaling
- eNOS Signaling
- Gap Junction Signaling
- Inhibition of Angiogenesis by TSP1
- Nitric Oxide Signaling in the Cardiovascular System
- Phototransduction Pathway
- Relaxin Signaling
- Sertoli Cell-Sertoli Cell Junction Signaling
- Sperm Motility
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- endometriosis
- suicide attempt
regulated by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm