SNX21 Gene Summary [Human]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | SNX21 |
| Official Name | sorting nexin family member 21 [Source:HGNC Symbol;Acc:HGNC:16154] |
| Ensembl ID | ENSG00000124104 |
| Bio databases IDs | |
| Aliases | sorting nexin family member 21 |
| Synonyms | 5730407K14Rik, AI481716, C20orf161, dJ337O18.4, PP3993, SNX-L, sorting nexin family member 21 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNX21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphatidylinositol-4,5-bisphosphate binding
- The Phox Homology domain, a phosphoinositide binding module
- protein binding
- tetratricopeptide repeat
- phosphatidylinositol binding
- PX domain
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SNX21 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein transport
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4,5-bisphosphate binding
- phosphatidylinositol-3-phosphate binding