PSG8 Gene Summary [Human]
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
Details
| Type | Protein Coding |
| Official Symbol | PSG8 |
| Official Name | pregnancy specific beta-1-glycoprotein 8 [Source:HGNC Symbol;Acc:HGNC:9525] |
| Ensembl ID | ENSG00000124467 |
| Bio databases IDs | |
| Aliases | pregnancy specific beta-1-glycoprotein 8 |
| Synonyms | pregnancy specific beta-1-glycoprotein 8, pregnancy specific β-1-glycoprotein 8, PSG1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PSG8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- Immunoglobulin V-set domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PSG8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- regulation of immune system process
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane
- cell surface