PRRG3 Gene Summary [Human]
This gene encodes a protein which contains a vitamin K-dependent carboxylation/gamma-carboxyglutamic domain. The encoded protein is a member of a family of vitamin K-dependent transmembrane proteins which contain a glutamate-rich extracellular domain. [provided by RefSeq, Aug 2011]
Details
| Type | Protein Coding |
| Official Symbol | PRRG3 |
| Official Name | proline rich and Gla domain 3 [Source:HGNC Symbol;Acc:HGNC:30798] |
| Ensembl ID | ENSG00000130032 |
| Bio databases IDs | |
| Aliases | proline rich and Gla domain 3 |
| Synonyms | Gm368, PRGP3, proline rich and Gla domain 3, proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane), RGD1560309, TMG3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PRRG3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PRRG3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding