Prrg3 Gene Summary [Mouse]
This gene encodes proline-rich gamma-carboxyglutamic acid protein 3, a member of vitamin K-dependent membrane proteins containing gamma-carboxyglutamic acid residues. The encoded precursor protein contains an N-terminal propeptide that is required for the carboxylation of glutamate residues in the mature protein. Alternate splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, Dec 2014]
Details
| Type | Protein Coding |
| Official Symbol | Prrg3 |
| Official Name | proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) [Source:MGI Symbol;Acc:MGI:2685214] |
| Ensembl ID | ENSMUSG00000033361 |
| Bio databases IDs | |
| Aliases | proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
| Synonyms | Gm368, PRGP3, proline rich and Gla domain 3, proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane), RGD1560309, TMG3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prrg3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prrg3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
Molecular Function
What the gene product does at the molecular level
- calcium ion binding