KLC4 Gene Summary [Human]

Predicted to be located in cytoplasm and microtubule. Predicted to be part of kinesin complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
KLC4
Official Name
kinesin light chain 4 [Source:HGNC Symbol;Acc:HGNC:21624]
Ensembl ID
ENSG00000137171
Bio databases IDs NCBI: 89953 Ensembl: ENSG00000137171
Aliases kinesin light chain 4
Synonyms 1200014P03Rik, bA387M24.3, kinesin light chain 4, KNSL8
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KLC4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • MalT-like TPR region
  • type IV pilus biogenesis/stability protein PilW
  • Tetratricopeptide repeats
  • protein binding
  • tetratricopeptide repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • ETV6-RUNX1
  • torkinib
  • PTPRR

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KLC4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule-based movement

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • kinesin complex
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • kinesin binding

Gene-Specific Assays for Results You Can Trust

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