TMEM14B Gene Summary [Human]
Enables identical protein binding activity. Involved in cerebral cortex development; neural precursor cell proliferation; and regulation of G1/S transition of mitotic cell cycle. Predicted to be integral component of membrane. Predicted to be active in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMEM14B |
| Official Name | transmembrane protein 14B [Source:HGNC Symbol;Acc:HGNC:21384] |
| Ensembl ID | ENSG00000137210 |
| Bio databases IDs | |
| Aliases | transmembrane protein 14B |
| Synonyms | transmembrane protein 14B |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM14B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- identical protein binding
- Transmembrane proteins 14C
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM14B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of heme biosynthetic process
- neural precursor cell proliferation
- regulation of G1/S transition of mitotic cell cycle
- cerebral cortex development
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding