FGFBP2 Gene Summary [Human]
This gene encodes a member of the fibroblast growth factor binding protein family. The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte-mediated immunity. An increase in the amount of gene product may be associated with atopic asthma and mild extrinsic asthma.[provided by RefSeq Staff, Oct 2008]
Details
| Type | Protein Coding |
| Official Symbol | FGFBP2 |
| Official Name | fibroblast growth factor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29451] |
| Ensembl ID | ENSG00000137441 |
| Bio databases IDs | |
| Aliases | fibroblast growth factor binding protein 2, killer-specific secretory protein of 37 kDa |
| Synonyms | fibroblast growth factor binding protein 2, HBP17RP, KSP37 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FGFBP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FGF binding protein 1 (FGF-BP1)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FGFBP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-cell signaling
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- growth factor binding
- protein binding