OIT3 Gene Summary [Human]
This gene was identified due to its downregulation in hepatocarcinomas. The encoded protein may be involved in liver development and function. [provided by RefSeq, Sep 2016]
Details
| Type | Protein Coding |
| Official Symbol | OIT3 |
| Official Name | oncoprotein induced transcript 3 [Source:HGNC Symbol;Acc:HGNC:29953] |
| Ensembl ID | ENSG00000138315 |
| Bio databases IDs | |
| Aliases | oncoprotein induced transcript 3, liver-specific ZP domain-containing protein |
| Synonyms | EF-9, FLJ39116, LZP, oncoprotein induced transcript 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OIT3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zona pellucida-like domain
- Zona pellucida (ZP) domain
- protein binding
- Coagulation Factor Xa inhibitory site
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OIT3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- renal system process
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding