IGSF6 Gene Summary [Human]

Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
IGSF6
Official Name
immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953]
Ensembl ID
ENSG00000140749
Bio databases IDs NCBI: 10261 Ensembl: ENSG00000140749
Aliases immunoglobulin superfamily member 6
Synonyms DORA, immunoglobulin superfamily member 6, immunoglobulin superfamily, member 6, ISGF6
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IGSF6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Immunoglobulin V-Type
  • immunoglobulin domain
  • Immunoglobulin like
  • transmembrane receptor
  • Immunoglobulin V-set domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • diethylstilbestrol
  • beta-estradiol
  • lipopolysaccharide
  • turmeric extract
  • 4-tert-octylphenol
  • methylprednisolone
  • ELOVL3
  • NFAT5
  • TCL1A
  • ShK-223

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human IGSF6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • immune response
  • cell surface receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • transmembrane signaling receptor activity

Gene-Specific Assays for Results You Can Trust

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