GPR32 Gene Summary [Human]
This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19. [provided by RefSeq, Nov 2012]
Details
| Type | Protein Coding |
| Official Symbol | GPR32 |
| Official Name | G protein-coupled receptor 32 [Source:HGNC Symbol;Acc:HGNC:4487] |
| Ensembl ID | ENSG00000142511 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 32, resolvin D1 receptor |
| Synonyms | DRV1, G protein-coupled receptor 32, RVDR1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR32 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the GPR32 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPR32 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- G-protein coupled receptor signaling pathway
- phospholipase C-activating G-protein coupled receptor signaling pathway
- complement receptor mediated signaling pathway
- elevation of cytosolic calcium ion concentration
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- complement receptor activity
- N-formyl peptide receptor activity