ZNF593 Gene Summary [Human]
Enables zinc ion binding activity. Involved in negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding activity and positive regulation of transcription by RNA polymerase II. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZNF593 |
| Official Name | zinc finger protein 593 [Source:HGNC Symbol;Acc:HGNC:30943] |
| Ensembl ID | ENSG00000142684 |
| Bio databases IDs | |
| Aliases | zinc finger protein 593 |
| Synonyms | 3110024A21Rik, E130106C14Rik, Zfp593, zinc finger protein 593, ZT86 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF593 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- zinc ion binding
- Zinc-finger double-stranded RNA-binding
- ribonucleoprotein binding
- U1 zinc finger
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF593 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosome biogenesis
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- zinc ion binding
- protein binding