MOB3C Gene Summary [Human]

The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
MOB3C
Official Name
MOB kinase activator 3C [Source:HGNC Symbol;Acc:HGNC:29800]
Ensembl ID
ENSG00000142961
Bio databases IDs NCBI: 148932 Ensembl: ENSG00000142961
Aliases MOB kinase activator 3C
Synonyms D130076I06RIK, MOB1E, Mob1 homolog 3C, MOB kinase activator 3C, MOBKL2C
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MOB3C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Mob1/phocein family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypertension
  • chronic kidney disease
regulated by
  • interferon alpha
  • TNF
regulates
role in cell
  • apoptosis
  • molecular cleavage in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MOB3C gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction
  • positive regulation of protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • protein kinase activator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.