GOLPH3L Gene Summary [Human]
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | GOLPH3L |
| Official Name | golgi phosphoprotein 3 like [Source:HGNC Symbol;Acc:HGNC:24882] |
| Ensembl ID | ENSG00000143457 |
| Bio databases IDs | |
| Aliases | golgi phosphoprotein 3 like |
| Synonyms | 2010204I15Rik, golgi phosphoprotein 3-like, GPP34R |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GOLPH3L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- Golgi phosphoprotein 3 (GPP34)
- protein binding
- phosphatidylinositol binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
- trans Golgi network
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GOLPH3L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retrograde vesicle-mediated transport, Golgi to ER
- Golgi organization
- Golgi to plasma membrane protein transport
- positive regulation of protein secretion
- Golgi vesicle budding
Cellular Component
Where in the cell the gene product is active
- trans-Golgi network
- Golgi cisterna membrane
- cytosol
- Golgi apparatus
- Golgi membrane
- Golgi cisterna
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4-phosphate binding
- protein binding