RETREG2 Gene Summary [Human]

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RETREG2
Official Name
reticulophagy regulator family member 2 [Source:HGNC Symbol;Acc:HGNC:28450]
Ensembl ID
ENSG00000144567
Bio databases IDs NCBI: 79137 Ensembl: ENSG00000144567
Aliases reticulophagy regulator family member 2
Synonyms C2orf17, FAM134A, MAG-2, MGC3035, reticulophagy regulator family member 2, RGD1306844
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RETREG2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding activity, bridging
  • protein binding
  • Arl6IP1_RETR3-like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • major depression
  • schizophrenia
  • non-insulin-dependent diabetes mellitus
regulated by
  • IFNA2
  • Immunoglobulin
  • mir-940
  • West Nile virus
regulates
  • collagen
role in cell
  • organization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Endoplasmic Reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RETREG2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • collagen catabolic process
  • endoplasmic reticulum organization

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.