DCP1B Gene Summary [Human]
This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Details
| Type | Protein Coding |
| Official Symbol | DCP1B |
| Official Name | decapping mRNA 1B [Source:HGNC Symbol;Acc:HGNC:24451] |
| Ensembl ID | ENSG00000151065 |
| Bio databases IDs | |
| Aliases | decapping mRNA 1B |
| Synonyms | B930050E02RIK, DCP1, decapping mRNA 1B, RGD1562214 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DCP1B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dcp1-like decapping family
- protein binding
- Pleckstrin homology-like domain
- mRNA-decapping enzyme C-terminus
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cytoplasmic mRNA processing body
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DCP1B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
- deadenylation-independent decapping of nuclear-transcribed mRNA
- deadenylation-dependent decapping of nuclear-transcribed mRNA
Cellular Component
Where in the cell the gene product is active
- nucleus
- intracellular membrane-bounded organelle
- membrane
- cytoplasmic mRNA processing body
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- mRNA binding
- enzyme activator activity