FLACC1 Gene Summary [Human]
Predicted to be located in cytoplasmic vesicle and sperm flagellum. Predicted to be active in cytoplasm; outer dense fiber; and sperm fibrous sheath. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | FLACC1 |
| Official Name | flagellum associated containing coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:14439] |
| Ensembl ID | ENSG00000155749 |
| Bio databases IDs | |
| Aliases | flagellum associated containing coiled-coil domains 1 |
| Synonyms | 4933425F06RIK, ALS2CR12, flagellum associated containing coiled-coil domains 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FLACC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- esophageal squamous cell carcinoma
- rheumatoid arthritis
- cutaneous melanoma
- epithelial cancer
- cutaneous melanoma cancer
- skin cancer
- melanoma cancer
- skin neoplasia
- seborrheic keratosis
- epithelial basal cell carcinoma
role in cell
- proliferation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- sperm tail
- outer dense fibers
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FLACC1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- outer dense fiber
- cytoplasm
- cytoplasmic vesicle
- sperm flagellum
Molecular Function
What the gene product does at the molecular level
- protein binding