NAA11 Gene Summary [Human]
Enables peptide alpha-N-acetyltransferase activity. Involved in N-terminal protein amino acid acetylation. Located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Part of NatA complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | NAA11 |
| Official Name | N-alpha-acetyltransferase 11, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:28125] |
| Ensembl ID | ENSG00000156269 |
| Bio databases IDs | |
| Aliases | N-alpha-acetyltransferase 11, NatA catalytic subunit |
| Synonyms | ARD1B, ARD2, hARD2, LOC105377298, N-alpha-acetyltransferase 11, NatA catalytic subunit, N(alpha)-acetyltransferase 11, NatA catalytic subunit, N-α-acetyltransferase 11, NatA catalytic subunit, N(α)-acetyltransferase 11, NatA catalytic subunit |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAA11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Acetyltransferase (GNAT) family
- peptide alpha-N-acetyltransferase
- NAT_SF
- Acetyltransferase (GNAT) domain
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- basal bodies
- centrosome
- Golgi Apparatus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NAA11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- N-terminal protein amino acid acetylation
Cellular Component
Where in the cell the gene product is active
- centrosome
- NatA complex
- cytoplasm
- cytosol
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- peptide alpha-N-acetyltransferase activity