SIGLEC16 Gene Summary [Human]
Predicted to enable sialic acid binding activity. Involved in positive regulation of defense response to bacterium and positive regulation of interleukin-6 production. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Polymorphic Pseudogene |
| Official Symbol | SIGLEC16 |
| Official Name | sialic acid binding Ig like lectin 16 [Source:HGNC Symbol;Acc:HGNC:24851] |
| Ensembl ID | ENSG00000161643 |
| Bio databases IDs | |
| Aliases | sialic acid binding Ig like lectin 16 |
| Synonyms | sialic acid binding Ig like lectin 16 (gene/pseudogene), SIGLECP16 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SIGLEC16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Immunoglobulin V-Type
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- Immunoglobulin V-set domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SIGLEC16 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
- positive regulation of interleukin-6 production
- positive regulation of defense response to bacterium
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- sialic acid binding
- carbohydrate binding