MYOZ3 Gene Summary [Human]
The protein encoded by this gene is specifically expressed in the skeletal muscle, and belongs to the myozenin family. Members of this family function as calcineurin-interacting proteins that help tether calcineurin to the sarcomere of cardiac and skeletal muscle. They play an important role in modulation of calcineurin signaling. [provided by RefSeq, Apr 2012]
Details
| Type | Protein Coding |
| Official Symbol | MYOZ3 |
| Official Name | myozenin 3 [Source:HGNC Symbol;Acc:HGNC:18565] |
| Ensembl ID | ENSG00000164591 |
| Bio databases IDs | |
| Aliases | myozenin 3, calsarcin 3, FATZ related protein 3 |
| Synonyms | 4833419K08Rik, AK056449, CS-3, FATZ-3, FRP3, LOC682470, myozenin 3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MYOZ3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calcineurin-binding protein (Calsarcin)
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Z line
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MYOZ3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- Z disc
- actin cytoskeleton
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin binding
- FATZ binding
- telethonin binding