SUN3 Gene Summary [Human]
Predicted to enable protein-membrane adaptor activity. Predicted to be involved in nuclear envelope organization. Predicted to be integral component of nuclear inner membrane. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | SUN3 |
| Official Name | Sad1 and UNC84 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22429] |
| Ensembl ID | ENSG00000164744 |
| Bio databases IDs | |
| Aliases | Sad1 and UNC84 domain containing 3 |
| Synonyms | C1, D630047F21, MGC33329, Sad1 and UNC84 domain containing 3, SUNC1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SUN3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sad1 / UNC-like C-terminal
- transmembrane domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SUN3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- nuclear inner membrane
- SUN-KASH complex
Molecular Function
What the gene product does at the molecular level
- protein anchor