METTL27 Gene Summary [Human]
This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | METTL27 |
| Official Name | methyltransferase like 27 [Source:HGNC Symbol;Acc:HGNC:19068] |
| Ensembl ID | ENSG00000165171 |
| Bio databases IDs | |
| Aliases | methyltransferase like 27 |
| Synonyms | AW492986, LOC687240, methyltransferase like 27, WBSCR27 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human METTL27 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme
- protein binding
- AdoMet_MTases
- methyltransferase domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human METTL27 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding