TMEM145 Gene Summary [Human]

Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMEM145
Official Name
transmembrane protein 145 [Source:HGNC Symbol;Acc:HGNC:26912]
Ensembl ID
ENSG00000167619
Bio databases IDs NCBI: 284339 Ensembl: ENSG00000167619
Aliases transmembrane protein 145
Synonyms B930076A02Rik, transmembrane protein 145
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM145 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein of unknown function (DUF3729)
  • Lung seven transmembrane receptor

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma formation
  • epithelial cancer
  • liver cancer
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
  • lung adenocarcinoma
  • hepatocellular carcinoma
  • chromophobe renal cell carcinoma
  • chromophobe renal cancer
  • invasive breast carcinoma
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMEM145 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • response to pheromone

Cellular Component

Where in the cell the gene product is active
  • membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.