MAJIN Gene Summary [Human]
Predicted to enable DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Predicted to be located in chromosome, telomeric region. Predicted to be integral component of nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MAJIN |
| Official Name | membrane anchored junction protein [Source:HGNC Symbol;Acc:HGNC:27441] |
| Ensembl ID | ENSG00000168070 |
| Bio databases IDs | |
| Aliases | membrane anchored junction protein |
| Synonyms | 1700123I01Rik, C11orf85, LOC100909430, LOC102550408, membrane anchored junction protein |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MAJIN often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-anchored junction protein
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- inner nuclear membrane
- nuclear envelope
- telomeres
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MAJIN gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- meiotic telomere clustering
- oogenesis
- spermatogenesis
- attachment of telomeric heterochromatin to nuclear envelope
- synapsis
Cellular Component
Where in the cell the gene product is active
- chromosome, telomeric region
- nuclear inner membrane
Molecular Function
What the gene product does at the molecular level
- DNA binding