CDC123 Gene Summary [Human]

Predicted to be involved in eukaryotic translation initiation factor 2 complex assembly and positive regulation of translational initiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CDC123
Official Name
cell division cycle 123 [Source:HGNC Symbol;Acc:HGNC:16827]
Ensembl ID
ENSG00000151465
Bio databases IDs NCBI: 8872 Ensembl: ENSG00000151465
Aliases cell division cycle 123
Synonyms C10orf7, cell division cycle 123, D123, G431001I09Rik
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDC123 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • D123
  • ATP binding
  • protein binding
  • magnesium ion binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • chronic obstructive pulmonary disease
  • COVID-19
  • coronary artery disease
  • diabetes mellitus
  • neuropathic pain
regulated by
  • sirolimus
  • valproic acid
  • beta-estradiol
  • trichostatin A
  • CSF2
  • torkinib
  • IL5
  • MTOR

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CDC123 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • magnesium ion binding
  • ATP binding
  • protein binding
  • protein binding involved in protein folding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.