TRMT61B Gene Summary [Human]
Enables mRNA (adenine-N1-)-methyltransferase activity; rRNA (adenine) methyltransferase activity; and tRNA (adenine-N1-)-methyltransferase activity. Involved in mRNA methylation; mitochondrial tRNA methylation; and protein homooligomerization. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TRMT61B |
| Official Name | tRNA methyltransferase 61B [Source:HGNC Symbol;Acc:HGNC:26070] |
| Ensembl ID | ENSG00000171103 |
| Bio databases IDs | |
| Aliases | tRNA methyltransferase 61B |
| Synonyms | tRNA methyltransferase 61B |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRMT61B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA (adenine)-methyltransferase
- enzyme
- protein binding
- AdoMet_MTases
- methyltransferase domain
- mRNA methyltransferase
- rRNA (adenine) methyltransferase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRMT61B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rRNA methylation
- mRNA processing
- tRNA methylation
Cellular Component
Where in the cell the gene product is active
- tRNA (m1A) methyltransferase complex
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding
- rRNA (adenine) methyltransferase activity