WIPF2 Gene Summary [Human]
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | WIPF2 |
| Official Name | WAS/WASL interacting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:30923] |
| Ensembl ID | ENSG00000171475 |
| Bio databases IDs | |
| Aliases | WAS/WASL interacting protein family member 2 |
| Synonyms | 1110014J05RIK, 5730509C05Rik, AA407487, Gm1176, RGD1561080, WAS/WASL interacting protein family member 2, WAS/WASL interacting protein family, member 2, WICH, WIRE |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human WIPF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Wiskott Aldrich syndrome homology region 2
- WH2
- protein binding
- WH2 motif
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human WIPF2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin binding