PRSS27 Gene Summary [Human]
This gene is located within a large protease gene cluster on chromosome 16. It belongs to the group-1 subfamily of serine proteases. The encoded protein is a secreted tryptic serine protease and is expressed mainly in the pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Details
| Type | Retained Intron |
| Official Symbol | PRSS27 |
| Official Name | serine protease 27 [Source:HGNC Symbol;Acc:HGNC:15475] |
| Ensembl ID | ENSG00000172382 |
| Bio databases IDs | |
| Aliases | serine protease 27, pancreasin, marapsin |
| Synonyms | CAPH2, MPN, PANCREASIN, serine protease 27 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PRSS27 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- peptidase
- Domain of unknown function (DUF1986)
Pathways
Biological processes and signaling networks where the PRSS27 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PRSS27 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- serine-type endopeptidase activity