TINCR Gene Summary [Human]
This gene produces a spliced long non-coding RNA that binds RNAs. This transcript interacts with staufen-1 protein to regulate the stability of mRNAs for genes involved in the differentiation of epidermal tissue. Variation in this gene may be associated with cancer progression. [provided by RefSeq, Aug 2017]
Details
| Type | Protein Coding |
| Official Symbol | TINCR |
| Official Name | TINCR ubiquitin domain containing [Source:HGNC Symbol;Acc:HGNC:14607] |
| Ensembl ID | ENSG00000223573 |
| Bio databases IDs | |
| Aliases | TINCR ubiquitin domain containing, non-protein coding RNA 36, long intergenic non-protein coding RNA 36, terminal differentiation-induced ncRNA |
| Synonyms | Gm20219, LINC00036, LOC134480470, NCRNA00036, onco-lncRNA-16, PLAC2, TINCR ubiquitin domain containing, TUBL |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TINCR often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubiquitin family
- Ubl1_cv_Nsp3_N-like
- Ubiquitin homologues
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetic nephropathy
- neoplasia
- lung adenocarcinoma
- epithelial cancer
- epithelial neoplasia
- cancer
- bladder cancer
- colorectal cancer
- metastasis
- organismal death
role in cell
- expression in
- proliferation
- apoptosis
- number
- degradation in
- phosphorylation in
- activation in
- migration
- growth
- formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown