NAA16 Gene Summary [Human]
Enables ribosome binding activity. Involved in N-terminal protein amino acid acetylation; negative regulation of apoptotic process; and protein stabilization. Located in cytosol. Part of NatA complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NAA16 |
| Official Name | N-alpha-acetyltransferase 16, NatA auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:26164] |
| Ensembl ID | ENSG00000172766 |
| Bio databases IDs | |
| Aliases | N-alpha-acetyltransferase 16, NatA auxiliary subunit |
| Synonyms | 1300019C06Rik, N-alpha-acetyltransferase 16, NatA auxiliary subunit, N(alpha)-acetyltransferase 16, NatA auxiliary subunit, NARG1L, N-α-acetyltransferase 16, NatA auxiliary subunit, N(α)-acetyltransferase 16, NatA auxiliary subunit |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAA16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR repeat
- N-terminal acetyltransferase A, auxiliary subunit
- ribosome binding
- enzyme
- protein binding
- acetyltransferase
- tetratricopeptide repeat
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NAA16 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- negative regulation of apoptotic process
- N-terminal peptidyl-methionine acetylation
- N-terminal protein amino acid acetylation
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- nucleus
- transcription factor complex
- NatA complex
- extracellular vesicular exosome
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- acetyltransferase activity
- ribosome binding