ZSCAN2 Gene Summary [Human]

The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
ZSCAN2
Official Name
zinc finger and SCAN domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20994]
Ensembl ID
ENSG00000176371
Bio databases IDs NCBI: 54993 Ensembl: ENSG00000176371
Aliases zinc finger and SCAN domain containing 2
Synonyms LOC90393, ZFP29, zinc finger and SCAN domain containing 2, ZNF854
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZSCAN2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • leucine rich region
  • transcription regulator
  • Zinc-finger double domain
  • SCAN domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • hypertrophic cardiomyopathy
  • bipolar disorder

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZSCAN2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • cell differentiation
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • RNA polymerase II regulatory region sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.