RMDN1 Gene Summary [Human]
Enables microtubule binding activity. Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle organization. Located in mitotic spindle pole and spindle microtubule. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RMDN1 |
| Official Name | regulator of microtubule dynamics 1 [Source:HGNC Symbol;Acc:HGNC:24285] |
| Ensembl ID | ENSG00000176623 |
| Bio databases IDs | |
| Aliases | regulator of microtubule dynamics 1 |
| Synonyms | 2410005O16Rik, 6430576D04Rik, AI449062, CGI-90, FAM82B, regulator of microtubule dynamics 1, RMD-1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RMDN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- spindle pole
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RMDN1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitotic spindle organization
- attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation
Cellular Component
Where in the cell the gene product is active
- spindle microtubule
- cytoplasm
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- microtubule binding