MAGEF1 Gene Summary [Human]
This intronless gene encodes a member of the MAGE superfamily. It is ubiquitously expressed in normal tissues and in tumor cells. This gene includes a microsatellite repeat in the coding region. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | MAGEF1 |
| Official Name | MAGE family member F1 [Source:HGNC Symbol;Acc:HGNC:29639] |
| Ensembl ID | ENSG00000177383 |
| Bio databases IDs | |
| Aliases | MAGE family member F1 |
| Synonyms | MAGE family member F1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MAGEF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MAGE homology domain
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MAGEF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
- negative regulation of double-strand break repair via homologous recombination
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding