EID1 Gene Summary [Human]
Enables histone acetyltransferase binding activity and histone acetyltransferase regulator activity. Involved in cell differentiation and negative regulation of transcription, DNA-templated. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasmic ribonucleoprotein granule and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | EID1 |
| Official Name | EP300 interacting inhibitor of differentiation 1 [Source:HGNC Symbol;Acc:HGNC:1191] |
| Ensembl ID | ENSG00000255302 |
| Bio databases IDs | |
| Aliases | EP300 interacting inhibitor of differentiation 1 |
| Synonyms | 2610002K20Rik, C15orf3, CRI1, EP300 interacting inhibitor of differentiation 1, IRO45620, ORF12, PNAS-22, PTD014, RBP21, RGD1562702 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EID1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- degron
- transcription co-repressor
- protein binding
- retinoblastoma protein binding domain
- histone acetyltransferase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic ribonucleoprotein granule
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EID1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transcription, DNA-dependent
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone acetyltransferase binding
- protein binding
- transcription corepressor activity