CYBC1 Gene Summary [Human]
Involved in innate immune response and respiratory burst after phagocytosis. Located in endoplasmic reticulum. Implicated in chronic granulomatous disease. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CYBC1 |
| Official Name | cytochrome b-245 chaperone 1 [Source:HGNC Symbol;Acc:HGNC:28672] |
| Ensembl ID | ENSG00000178927 |
| Bio databases IDs | |
| Aliases | cytochrome b-245 chaperone 1 |
| Synonyms | C17orf62, CGD5, cytochrome b-245 chaperone 1, Eros |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CYBC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cytochrome b-245 chaperone 1 / Eros
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CYBC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- respiratory burst after phagocytosis
- innate immune response
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding