GIMAP7 Gene Summary [Human]

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
GIMAP7
Official Name
GTPase, IMAP family member 7 [Source:HGNC Symbol;Acc:HGNC:22404]
Ensembl ID
ENSG00000179144
Bio databases IDs NCBI: 168537 Ensembl: ENSG00000179144
Aliases GTPase, IMAP family member 7, immune-associated nucleotide-binding protein 7
Synonyms GTPase, IMAP family member 7, hIAN7, IAN7
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GIMAP7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • GTP binding
  • 50S ribosome-binding GTPase
  • protein homodimerization
  • GTPase
  • enzyme
  • protein binding
  • identical protein binding
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • AIG1 family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • lung cancer
  • systemic sclerosis
  • chronic periodontal disease
regulated by
  • lipopolysaccharide
  • SYK
  • NKX2-3
  • Ebna3c
  • aldesleukin
  • HIV-1 BaL
regulates
  • guanosine triphosphate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • lipid droplets

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GIMAP7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • GTP metabolic process

Cellular Component

Where in the cell the gene product is active
  • lipid particle
  • endoplasmic reticulum
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • identical protein binding
  • protein binding
  • protein homodimerization activity
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.