TIGD2 Gene Summary [Human]
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | TIGD2 |
| Official Name | tigger transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:18333] |
| Ensembl ID | ENSG00000180346 |
| Bio databases IDs | |
| Aliases | tigger transposable element derived 2 |
| Synonyms | 3632410O17Rik, HEL106, LOC100912924, LOC102556876, LOC108348248, RGD1559612, tigger transposable element derived 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TIGD2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DDE superfamily endonuclease
- Tc5 transposase DNA-binding domain
- CENP-B N-terminal DNA-binding domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TIGD2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding