CEP97 Gene Summary [Human]

Predicted to enable calmodulin binding activity. Involved in negative regulation of cilium assembly and regulation of mitotic spindle assembly. Located in centriolar satellite and cytosol. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Retained Intron
Official Symbol
CEP97
Official Name
centrosomal protein 97 [Source:HGNC Symbol;Acc:HGNC:26244]
Ensembl ID
ENSG00000182504
Bio databases IDs NCBI: 79598 Ensembl: ENSG00000182504
Aliases centrosomal protein 97
Synonyms 2810403B08RIK, 4932439K18Rik, centrosomal protein 97, E130116N02Rik, LRRIQ2, RGD1307400
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CEP97 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • leucine-rich repeat
  • IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
  • protein phosphatase 1 regulatory subunit 42
  • Leucine rich repeat
  • protein binding
  • Leucine Rich repeats (2 copies)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
regulates
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centrosome
  • centriole
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CEP97 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell projection organization

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • centriole
  • cytosol
  • macromolecular complex

Molecular Function

What the gene product does at the molecular level
  • calmodulin binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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