LRRC55 Gene Summary [Human]

Enables potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Involved in positive regulation of voltage-gated potassium channel activity and potassium ion transmembrane transport. Part of voltage-gated potassium channel complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
LRRC55
Official Name
leucine rich repeat containing 55 [Source:HGNC Symbol;Acc:HGNC:32324]
Ensembl ID
ENSG00000183908
Bio databases IDs NCBI: 219527 Ensembl: ENSG00000183908
Aliases leucine rich repeat containing 55
Synonyms A330097E02Rik, Gm351, leucine rich repeat containing 55
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LRRC55 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Leucine-rich repeats, outliers
  • Leucine-rich repeats, typical (most populated) subfamily
  • channel regulator
  • voltage-gated potassium channel
  • potassium channel regulator
  • ion channel binding
  • Leucine rich repeat
  • Leucine rich repeat C-terminal domain
  • Leucine rich repeat N-terminal domain
  • ion channel

Pathways

Biological processes and signaling networks where the LRRC55 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rosacea
regulated by
regulates
  • BK
  • BK channel
  • K+
role in cell
  • activation in
  • injury

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LRRC55 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • voltage-gated potassium channel complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • voltage-gated potassium channel activity
  • ion channel binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.