ZNF93 Gene Summary [Human]

Enables DNA-binding transcription factor activity. Involved in negative regulation of transcription, DNA-templated and negative regulation of transposon integration. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
ZNF93
Official Name
zinc finger protein 93 [Source:HGNC Symbol;Acc:HGNC:13169]
Ensembl ID
ENSG00000184635
Bio databases IDs NCBI: 81931 Ensembl: ENSG00000184635
Aliases zinc finger protein 93
Synonyms HPF34, HTF34, TF34, zinc finger protein 93, ZNF505
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF93 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • krueppel associated box
  • transcription regulator
  • RNA polymerase II transcription regulatory region sequence-specific binding transcriptional repressor activity
  • Zinc-finger double domain
  • KRAB (Kruppel-associated box) domain -A box

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • acute myeloid leukemia
  • chronic periodontal disease

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZNF93 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription from RNA polymerase II promoter
  • negative regulation of transposition, RNA-mediated
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • sequence-specific DNA binding transcription factor activity
  • zinc ion binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.